The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 11074 malaria professionals are enjoying the free benefits of MalariaWorld today


NOT Open Access |Monoclonal antibodies show promise in phase I malaria trial

September 14, 2021 - 09:15 -- NOT Open Access
Mullard A
Nat Rev Drug Discov. 2021 Sep 6

The US National Institute of Allergy and Infectious Diseases hopes that a monoclonal antibody may provide a means of reducing the impact of malaria.

Adaptive interventions for optimizing malaria control: an implementation study protocol for a block-cluster randomized, sequential multiple assignment trial

July 21, 2020 - 15:36 -- Open Access
Zhou G, Lee MC, Atieli HE, Githure JI, Githeko AK, Kazura JW, Yan G
Trials. 2020 Jul 20;21(1):665

In the past two decades, the massive scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has led to significant reductions in malaria mortality and morbidity. Nonetheless, the malaria burden remains high, and a dozen countries in Africa show a trend of increasing malaria incidence over the past several years. This underscores the need to improve the effectiveness of interventions by optimizing first-line intervention tools and integrating newly approved products into control programs. Because transmission settings and vector ecologies vary from place to place, malaria interventions should be adapted and readapted over time in response to evolving malaria risks. An adaptive approach based on local malaria epidemiology and vector ecology may lead to significant reductions in malaria incidence and transmission risk.

Subscribe to RSS - trial