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childhood disease

NOT Open Access | Pediatric Cerebral Malaria

October 30, 2021 - 12:01 -- NOT Open Access
Author(s): 
Guenther G, Muller D, Moyo D, Postels D
Reference: 
Curr Trop Med Rep. 2021 Jun;8(2):69-80

Malaria is the most important parasitic disease of humankind. Cerebral malaria is malaria’s deadliest clinical manifestation and has a profound public health impact in endemic areas. In Africa, it is primarily a disease of childhood. Here we review recent updates in research into cerebral malaria pathogenesis, clinical care, treatment, and prevention.

Glucose-6-phosphate dehydrogenase deficiency and susceptibility to childhood diseases in Kilifi, Kenya

December 8, 2020 - 10:52 -- Open Access
Author(s): 
Uyoga S, Macharia AW, Ndila CM, Nyutu G, Shebe M, Awuondo KO, Mturi N, Peshu N, Tsofa B, Scott JAG, Maitland K, Williams TN
Reference: 
Blood Adv. 2020 Dec 8;4(23):5942-5950

Few previous studies have reported the effects of glucose-6-phosphate dehydrogenase (G6PD)-deficiency on child health in Africa. We conducted a case-control study in which cases (n = 6829) were children admitted, for any reason, to Kilifi County Hospital, Kenya, while controls (n = 10 179) were recruited from the surrounding community. Cases were subclassified based on their clinical and laboratory findings at admission.

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