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NOT Open Access | Magnetic Resonance Imaging of Cerebral Malaria

March 17, 2021 - 09:10 -- NOT Open Access
Sandip S, Chandrashekhara SH
Indian J Pediatr. 2021 Mar 11

A 10-y-old boy presented with history of on and off fever with rigor for one week followed by altered sensorium. Brain magnetic resonance imaging (MRI) revealed abnormal areas of hyperintensities on T2-weighted images involving bilateral thalami, bilateral external capsule, midbrain, pons, cerebellar peduncles, and splenium.

Brain Magnetic Resonance Imaging Reveals Different Courses of Disease in Pediatric and Adult Cerebral Malaria

December 16, 2020 - 12:16 -- Open Access
Sahu PK, Hoffmann A, Wassmer SC, et al.
Clin Infect Dis. 2020 Dec 16:ciaa1647

Cerebral malaria is a common presentation of severe Plasmodium falciparum infection and remains an important cause of death in the tropics. Key aspects of its pathogenesis are still incompletely understood, but severe brain swelling identified by magnetic resonance imaging (MRI) was associated with a fatal outcome in African children. In contrast, neuroimaging investigations failed to identify cerebral features associated with fatality in Asian adults.

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