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Culturable bacteria associated with Anopheles darlingi and their paratransgenesis potential

January 13, 2021 - 10:25 -- Open Access
Elerson Matos Rocha, Osvaldo Marinotti, Wanderli Pedro Tadei, et al.
Malaria Journal 2021 20:40, 13 January 2021

Malaria remains a major public health problem in South America, mostly in the Amazon region. Among newly proposed ways of controlling malaria transmission to humans, paratransgenesis is a promising alternative. Paratransgenesis aims to inhibit the development of parasites within the vector through the action of genetically modified bacteria. The first step towards successful paratransgenesis in the Amazon is the identification of Anopheles darlingi symbiotic bacteria, which are transmitted vertically among mosquitoes, and are not pathogenic to humans.

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