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Sensitive detection of Plasmodium vivax malaria by the rotating-crystal magneto-optical method in Thailand

September 25, 2021 - 11:46 -- Open Access
Orbán Á, Longley RJ, Sripoorote P, Maneechai N, Nguitragool W, Butykai Á, Mueller I, Sattabongkot J, Karl S, Kézsmárki I
Sci Rep. 2021 Sep 17;11(1):18547

The rotating-crystal magneto-optical detection (RMOD) method has been developed for the rapid and quantitative diagnosis of malaria and tested systematically on various malaria infection models. Very recently, an extended field trial in a high-transmission region of Papua New Guinea demonstrated its great potential for detecting malaria infections, in particular Plasmodium vivax.

Magneto-optical diagnosis of symptomatic malaria in Papua New Guinea

February 15, 2021 - 15:32 -- Open Access
Arndt L, Koleala T, Karl S, et al.
Nat Commun. 2021 Feb 12;12(1):969

Improved methods for malaria diagnosis are urgently needed. Here, we evaluate a novel method named rotating-crystal magneto-optical detection (RMOD) in 956 suspected malaria patients in Papua New Guinea. RMOD tests can be conducted within minutes and at low cost. We systematically evaluate the capability of RMOD to detect infections by directly comparing it with expert light microscopy, rapid diagnostic tests and polymerase chain reaction on capillary blood samples.

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