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label-free imaging

Label-free imaging and classification of live P. falciparum enables high performance parasitemia quantification without fixation or staining

August 10, 2021 - 17:49 -- Open Access
Lebel P, Dial R, Vemuri VNP, Garcia V, DeRisi J, Gómez-Sjöberg R
PLoS Comput Biol. 2021 Aug 9;17(8):e1009257

Manual microscopic inspection of fixed and stained blood smears has remained the gold standard for Plasmodium parasitemia analysis for over a century. Unfortunately, smear preparation consumes time and reagents, while manual microscopy is skill-dependent and labor-intensive.

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