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Malaria vaccine roller coaster

October 16, 2021 - 20:15 -- Open Access
Nkumama IN, Osier FHA
Nat Microbiol. 2021 Oct 11

Malaria vaccine development has been characterised by excitement and disappointment in equal measure. Candidates that have shown promise in pre-clinical animal models and phase 1/2 clinical trials in volunteers who are malaria naive typically do not make the grade when tested in malaria-endemic populations.

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