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Evaluation of different deployment strategies for larviciding to control malaria: a simulation study

July 28, 2021 - 15:03 -- Open Access
Manuela Runge, Salum Mapua, Ismail Nambunga, Thomas A. Smith, Nakul Chitnis, Fredros Okumu and Emilie Pothin
Malaria Journal 2021 20:324, 27 July 2021

Larviciding against malaria vectors in Africa has been limited to indoor residual spraying and insecticide-treated nets, but is increasingly being considered by some countries as a complementary strategy. However, despite progress towards improved larvicides and new tools for mapping or treating mosquito-breeding sites, little is known about the optimal deployment strategies for larviciding in different transmission and seasonality settings.

Agent-based modelling of complex factors impacting malaria prevalence

April 21, 2021 - 14:33 -- Open Access
Miracle Amadi, Anna Shcherbacheva and Heikki Haario
Malaria Journal 2021 20:185, 15 April 2021

Increasingly complex models have been developed to characterize the transmission dynamics of malaria. The multiplicity of malaria transmission factors calls for a realistic modelling approach that incorporates various complex factors such as the effect of control measures, behavioural impacts of the parasites to the vector, or socio-economic variables. Indeed, the crucial impact of household size in eliminating malaria has been emphasized in previous studies. However, increasing complexity also increases the difficulty of calibrating model parameters. Moreover, despite the availability of much field data, a common pitfall in malaria transmission modelling is to obtain data that could be directly used for model calibration.

Inference and prediction of malaria transmission dynamics using time series data

July 20, 2020 - 15:30 -- Open Access
Shi B, Lin S, Tan Q, Cao J, Zhou X, Xia S, Zhou XN, Liu J
Infect Dis Poverty. 2020 Jul 16;9(1):95

Disease surveillance systems are essential for effective disease intervention and control by monitoring disease prevalence as time series. To evaluate the severity of an epidemic, statistical methods are widely used to forecast the trend, seasonality, and the possible number of infections of a disease. However, most statistical methods are limited in revealing the underlying dynamics of disease transmission, which may be affected by various impact factors, such as environmental, meteorological, and physiological factors. In this study, we focus on investigating malaria transmission dynamics based on time series data.

NOT Open Access | A Malaria Transmission Model Predicts Holoendemic, Hyperendemic, and Hypoendemic Transmission Patterns Under Varied Seasonal Vector Dynamics

November 27, 2019 - 15:58 -- NOT Open Access
Ratti V, Wallace DI
Journal of Medical Entomology, tjz186

A model is developed of malaria (Plasmodium falciparum) transmission in vector (Anopheles gambiae) and human populations that include the capacity for both clinical and parasite suppressing immunity. This model is coupled with a population model for Anopheles gambiae that varies seasonal with temperature and larval habitat availability. At steady state, the model clearly distinguishes uns hypoendemic transmission patterns from stable hyperendemic and holoendemic patterns of transmission.

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