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Liver and kidney dysfunction, hypoglycemia, and thrombocytopenia in Plasmodium vivax malaria patients at a Colombian Northwest region

October 30, 2021 - 13:17 -- Open Access
Tovar-Acero C, Velasco MC, Avilés-Vergara PA, Ricardo-Caldera DM, Alvis EM, Ramirez-Montoya J, Yasnot Acosta MF
Parasite Epidemiol Control. 2021 Jan 25;13:e00203

Plasmodium vivax has high morbidity, it is the Plasmodium species with the greatest worldwide distribution, and its ability to trigger severe symptoms is currently recognized. The present study aims to compare the clinical and epidemiological characteristics of patients with P. vivax malaria, with and without complication criteria, in an endemic area for malaria transmission in northwest Colombia.

Meta-analysis of the prevalence of malaria associated with pregnancy in Colombia 2000-2020

August 4, 2021 - 16:04 -- Open Access
Cardona-Arias JA, Carmona-Fonseca J
PLoS One. 2021 Jul 30;16(7):e0255028

Knowledge about malaria associated with pregnancy is scarce in Latin America, and in Colombia, little is known about the magnitude of this infection. A systematic review was conducted to determine the prevalence of malaria associated with pregnancy (MAP) and each of its three forms: gestational (GM), placental (PM), and congenital (CM) tested using thick blood smear (TBS) and PCR. Also to compare the proportion of cases due to Plasmodium falciparum and Plasmodium vivax in Colombia from the year 2000-2020.

NOT Open Access | Plasmodium vivax and Neisseria meningitidis co-infection in a newborn

June 1, 2021 - 15:24 -- NOT Open Access
Ordoñez Díaz KM, Gutiérrez Paternina JJ
Trop Doct. 2021 May 27:494755211017419

Invasive infections due to Neisseria meningitidis in Colombia are unusual in newborns, in contrast to infections due to Plasmodium vivax which is one of the main pathogens related to the presentation of fever in this age group, especially in the indigenous population.

Malaria risk stratification in Colombia 2010 to 2019

March 17, 2021 - 17:17 -- Open Access
Padilla-Rodríguez JC, Olivera MJ, Ahumada-Franco ML, Paredes-Medina AE
PLoS One. 2021 Mar 11;16(3):e0247811

Heterogeneity and focalization are the most common epidemiological characteristics of endemic countries in the Americas, where malaria transmission is moderate and low. During malaria elimination, the first step is to perform a risk stratification exercise to prioritize interventions. This study aimed to identify malaria risk strata in the ecoepidemiological regions of Colombia.

NOT Open Access | Malaria among migrants in a university hospital in Colombia during 2018: A case series

December 30, 2020 - 13:47 -- NOT Open Access
Carreño-Almánzar FR, Coronado-Galán A, Cala-Gómez SA, Vega-Vera A
Trop Doct. 2020 Dec 23:49475520981301

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia.

NOT Open Access | Association of variants in IL1B, TLR9, TREM1, IL10RA, and CD3G and Native American ancestry on malaria susceptibility in Colombian populations

December 16, 2020 - 09:44 -- NOT Open Access
Mario-Vásquez JE, Naranjo-González CA, Montiel J, Zuluaga LM, Vásquez AM, Tobón-Castaño A, Bedoya G, Segura C
Infect Genet Evol. 2020 Dec 11:104675

Host genetics is an influencing factor in the manifestation of infectious diseases. In this study, the association of mild malaria with 28 variants in 16 genes previously reported in other populations and/or close to ancestry-informative markers (AIMs) selected was evaluated in an admixed 736 Colombian population sample. Additionally, the effect of genetic ancestry on phenotype expression was explored.

NOT Open Access | State of Artemisinin and Partner Drug Susceptibility in Plasmodium falciparum Clinical Isolates from Colombia

December 9, 2020 - 07:51 -- NOT Open Access
Montenegro LM, de Las Salas B, Neal AT, Tobon-Castaño A, Fairhurst RM, Lopera-Mesa TM
Am J Trop Med Hyg. 2020 Dec 7

Delayed parasite clearance time observed in Southeast Asia provided the first evidence of Plasmodium falciparum resistance to artemisinins. The ex vivo ring-stage survival assay (RSA) mimics parasite exposure to pharmacologically relevant artemisinin concentrations. Mutations in the C-terminal propeller domain of the putative kelch protein Pf3D7_1343700 (K13) are associated with artemisinin resistance.

Strategies for malaria elimination: an Afro-Colombian perspective

November 19, 2020 - 13:00 -- Open Access
Knudson-Ospina A, Barreto-Zorza YM, Castillo CF, Y Mosquera L, Apráez-Ippolito G, Olaya-Másmela LA, Piamba AH, Sanchez R
Rev Salud Publica (Bogota). 2020 Nov 13;21(1):9-16

To describe strategies for malaria elimination based on the perception of Afro-Colombian residents in Guapi, in the context of the Integrated Management Strategy for the Promotion, Prevention and Control of Vector-Borne Diseases in Colombia (EGI-ETV).

Cost-effectiveness of rapid diagnostic tests, compared to microscopic tests, for the diagnosis and treatment of gestational malaria in Colombia from an institutional perspective

November 11, 2020 - 14:22 -- Open Access
Deisy Cristina Restrepo-Posada, Jaime Carmona-Fonseca and Jaiberth Antonio Cardona-Arias
Malaria Journal 2020 19:400, 10 November 2020

Gestational malaria is associated with negative outcomes in maternal and gestational health; timely diagnosis is crucial to avoid complications. However, the limited infrastructure, equipment, test reagents, and trained staff make it difficult to use thick blood smear tests in rural areas, where rapid testing could be a viable alternative. The purpose of this study was to estimate the cost-effectiveness of rapid tests type III (Plasmodium falciparum/Plasmodium spp P.f/pan) versus microscopic tests for the diagnosis and treatment of gestational malaria in Colombia.

Effect of land cover and landscape fragmentation on anopheline mosquito abundance and diversity in an important Colombian malaria endemic region

October 20, 2020 - 16:05 -- Open Access
Hernández-Valencia JC, Rincón DS, Marín A, Naranjo-Díaz N, Correa MM
PLoS One. 2020 Oct 15;15(10):e0240207

Landscape structure influences the distribution and abundance of anopheline mosquitoes and has an indirect impact on malaria transmission. This work aimed to determine the effect of land cover and landscape fragmentation on anopheline mosquito abundance and diversity in an important Colombian malaria endemic area, the Bajo Cauca region.


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