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Scientific Articles

Open Access | Ranking Malaria Risk Factors to Guide Malaria Control Efforts in African Highlands

December 15, 2009 - 20:37 -- Ingeborg van Schayk
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Author(s): 
Protopopoff N, Van Bortel W, Speybroeck N, Van Geertruyden J-P, Baza D, et al.
Reference: 
PLoS ONE 4(11): e8022

A better understanding of the factors impacting transmission in the highlands is crucial to improve well targeted malaria control strategies.

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Open Access | Editorial: Time for a “Third Wave” of Malaria Activism to Tackle the Drug Stock-out Crisis

December 15, 2009 - 13:53 -- Ingeborg van Schayk
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Author(s): 
The PLoS Medicine Editors
Reference: 
PLoS Med 6(11): e1000188

The PLoS Medicine Editors discuss shortages of artemisinin-based combination therapy in Africa at the point of care and how these can be addressed.

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Open Access | A rapid malaria appraisal in the Venezuelan Amazon

December 14, 2009 - 13:52 -- Ingeborg van Schayk
Author(s): 
Wolfram G Metzger, Anibal M Giron, Sarai Vivas-Martinez, Julio Gonzalez, Antonio J Charrasco, Benjamin G Mordmuller, Magda Magris
Reference: 
Malaria Journal 2009, 8:291 (11 December 2009)

Using a rapid malaria appraisal method, the objective of the study was to provide baseline data about malaria and malaria control in Amazonas State. The authors conclude that malaria control is possible, even in tropical rain forest areas, if the health system is working adequately.

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Open Access | A replication study of the association between the IL12B promoter allele CTCTAA and susceptibility to cerebral malaria in Thai population

December 14, 2009 - 13:48 -- Ingeborg van Schayk
Author(s): 
Izumi Naka, Jintana Patarapotikul, Katsushi Tokunaga, Hathairad Hananantachai, Naoyuki Tsuchiya, Jun Ohashi
Reference: 
Malaria Journal 2009, 8:290 (11 December 2009)

The aim of the study was to better define SNPs in the 5q31 genomic region that could be associated with severe malaria.

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Open Access | Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base

December 14, 2009 - 13:43 -- Ingeborg van Schayk
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Author(s): 
Olivier Bouchaud, Patrick Imbert, Jean-Etienne Touze, Alex NO Dodoo, Martin Danis, Fabrice Legros
Reference: 
Malaria Journal 2009, 8:289 (10 December 2009)

Halofantrine (HF) was considered an effective and safe treatment for multi-drug resistant falciparum malaria until 1993, when the first case of drug-associated death was reported.

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Open Access | A malaria outbreak in Naxalbari, Darjeeling district, West Bengal, India, 2005: weaknesses in disease control, important risk factors

December 14, 2009 - 13:38 -- Ingeborg van Schayk
Author(s): 
Puran K Sharma, Ramakrishnan Ramanchandran, Yvan J Hutin, Raju Sharma, Mohan D Gupte
Reference: 
Malaria Journal 2009, 8:288 (10 December 2009)

An outbreak of malaria in Naxalbari, West Bengal, India, in 2005 was investigated to understand determinants and propose control measures.

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Open Access | The use of mobile phone data for the estimation of the travel patterns and imported Plasmodium falciparum rates among Zanzibar residents

December 14, 2009 - 11:57 -- Ingeborg van Schayk
Author(s): 
Andrew J Tatem, Youliang Qiu, David L Smith, Oliver Sabot, Abdullah S Ali, Bruno Moonen
Reference: 
Malaria Journal 2009, 8:287 (10 December 2009)

In combination with spatial data on malaria endemicity and transmission models, movement patterns derived from phone records can inform on the likely sources and rates of malaria importation.

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Open Access | IL4 gene polymorphism and previous malaria experiences manipulate anti-Plasmodium falciparum antibody isotype profiles in complicated and uncomplicated malaria

December 14, 2009 - 11:49 -- Ingeborg van Schayk
Author(s): 
Piyatida Tangteerawatana, Hedvig Perlmann, Masashi Hayano, Thareerat Kalambaheti, Marita Troye-Blomberg, Srisin Khusmith
Reference: 
Malaria Journal 2009, 8:286 (10 December 2009)

The results suggest that IL4-590C or T alleles participated differently in the regulation of anti-malarial antibody isotype profiles in primary and secondary malaria infection and, therefore, could play an important role in alteration of malaria severity.

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Open Access | A microarray-based system for the simultaneous analysis of single nucleotide polymorphisms in human genes involved in the metabolism of anti-malarial drugs

December 14, 2009 - 11:45 -- Ingeborg van Schayk
Author(s): 
Eva-Maria Hodel, Serej D Ley, Weihong Qi, Frederic Ariey, Blaise Genton, Hans-Peter Beck
Reference: 
Malaria Journal 2009, 8:285 (9 December 2009)

The major limit of the microarray technology for this purpose was lack of robustness and with a large number of missing data or with incorrect specificity.

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Open Access | Multiplex real-time quantitative PCR, microscopy and rapid diagnostic immuno-chromatographic tests for the detection of Plasmodium spp: performance, limit of detection analysis and quality assurance

December 14, 2009 - 11:40 -- Ingeborg van Schayk
Author(s): 
Krishna Khairnar, Donald Martin, Rachel Lau, Filip Ralevski, Dylan R Pillai
Reference: 
Malaria Journal 2009, 8:284 (9 December 2009)

Multiplex QPCR but not ICTs are an essential adjunct to microscopy in the reference laboratory detection of malaria species specifically due to the superior LOD.

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