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Scientific Articles

Intermittent preventive treatment of malaria in pregnancy (IPTp): participation of community-directed distributors of ivermectin for onchocerciasis improves IPTp access in Ugandan rural communities

November 26, 2009 - 06:58 -- Kabogo Ndegwa
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Author(s): 
Richard Ndyomugyenyi, Ephraim Tukesiga, James Katamanywa
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1221-1228, doi:10.1016/j.trstmh.2009.03.006

Access and compliance to sulfadoxine–pyrimethamine (SP) for intermittent preventive treatment of malaria in pregnancy (IPTp) when delivered by community-directed drug distributors (CDDs) of ivermectin for onchocerciasis control (intervention arm) and through delivery of SP–IPTp during antenatal care visit (control arm) was investigated in western Uganda.

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Nucleotide sequence polymorphism at the apical membrane antigen-1 locus reveals population history of Plasmodium vivax in Thailand

November 26, 2009 - 06:55 -- Patrick Sampao
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Author(s): 
Chaturong Putaporntip, Somchai Jongwutiwes, Priscila Grynberg, Liwang Cui, Austin L. Hughes.
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Infection, Genetics and Evolution, Volume 9, Issue 6, December 2009, Pages 1295-1300, doi:10.1016/j.meegid.2009.07.005.

Apical membrane antigen-1 is a candidate for inclusion in a vaccine for the human malaria parasite Plasmodium vivax.

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Recurrence rate of vivax malaria in the Republic of Korea

November 26, 2009 - 06:53 -- Kabogo Ndegwa
Author(s): 
Ki Tae Moon, Young Keun Kim, Dong Hoon Ko, Inho Park, Dong Chun Shin, Changsoo Kim.
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1245-1249, doi:10.1016/j.trstmh.2008.10.023

In the Republic of Korea (ROK), military antimalarial chemoprophylaxis was initiated in 1997. Although chemoprophylaxis reduces malaria cases, long-term chemoprophylaxis could increase resistance. In this study, the recurrence rate of vivax malaria was investigated.

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Short communication: Absence of an impact of resistance to chloroquine on consultations for malaria in Niakhar, Senegal (1992–2004)

November 26, 2009 - 06:50 -- Kabogo Ndegwa
Author(s): 
A. Munier, A. Diallo, J.P. Chippaux
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1288-1290, doi:10.1016/j.trstmh.2009.03.017

We retrospectively assessed the impact of chloroquine (CQ) resistance in the rural region of Niakhar, Senegal, where resistance to CQ emerged in 1992, from increases in consultations and returns of patients to the health centre following antimalarial treatment.

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Short communication: IFNGR1 polymorphisms in Thai malaria patients

November 26, 2009 - 06:50 -- Patrick Sampao
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Author(s): 
Izumi Naka, Jintana Patarapotikul, Hathairad Hananantachai, Katsushi Tokunaga, Naoyuki Tsuchiya, Jun Ohashi
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Infection, Genetics and Evolution, Volume 9, Issue 6, December 2009, Pages 1406-1409, doi:10.1016/j.meegid.2009.08.004

Interferon-γ (IFN-γ) has been suggested to play an important role in the pathogenesis of malaria.

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Mini review: A new global malaria eradication strategy: implications for malaria research from an Indian perspective

November 26, 2009 - 06:48 -- Kabogo Ndegwa
Author(s): 
Neeru Singh
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1202-1203, doi:10.1016/j.trstmh.2009.04.023

The Roll Back Malaria Partnership has developed the Global Malaria Action Plan for a substantial reduction in the burden of malaria and its eradication in the long term.

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The action of falciparum malaria on the human and chimpanzee genomes compared: Absence of evidence for a genomic signature of malaria at HBB and G6PD in three subspecies of chimpanzee

November 26, 2009 - 06:45 -- Patrick Sampao
Author(s): 
T.S. MacFie, E. Nerrienet, R.E. Bontrop, N.I. Mundy
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Infection, Genetics and Evolution, Volume 9, Issue 6, December 2009, Pages 1248-1252, doi:10.1016/j.meegid.2009.06.025

Here we investigate whether the genomic signatures of plasmodial infection found in humans are also present in chimpanzees.

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Microfinance against malaria: impact of Freedom from Hunger's malaria education when delivered by rural banks in Ghana

November 26, 2009 - 06:45 -- Kabogo Ndegwa
Author(s): 
Natalie De La Cruz, Benjamin Crookston, Bobbi Gray, Steve Alder, Kirk Dearden
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1229-1236, doi:10.1016/j.trstmh.2009.03.018

Results indicate that, although significant barriers to malaria control remain, a malaria education program provided by microfinance institutions can effectively contribute to community and national malaria initiatives.

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Individual, household and environmental risk factors for malaria infection in Amhara, Oromia and SNNP regions of Ethiopia

November 26, 2009 - 06:43 -- Kabogo Ndegwa
Author(s): 
Patricia M. Graves, Frank O. Richards, Jeremiah Ngondi, Paul M. Emerson, Estifanos Biru Shargie, Tekola Endeshaw, Pietro Ceccato, Yeshewamebrat Ejigsemahu, Aryc W. Mosher, Afework Hailemariam, Mulat Zerihun, Tesfaye Teferi, Berhan Ayele, Ayenew Mesele, Gideon Yohannes, Abate Tilahun, Teshome Gebre
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Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 103, Issue 12, December 2009, Pages 1211-1220, doi:10.1016/j.trstmh.2008.11.016

We assessed malaria infection in relation to age, altitude, rainfall, socio-economic factors and coverage of control measures in a representative sample of 11 437 people in Amhara, Oromia and SNNP regions of Ethiopia in December 2006–January 2007.

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A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity

November 26, 2009 - 06:41 -- Patrick Sampao
Author(s): 
Stefano Guglielmo, Massimo Bertinaria, Barbara Rolando, Marco Crosetti, Roberta Fruttero, Vanessa Yardley, Simon L. Croft, Alberto Gasco
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European Journal of Medicinal Chemistry, Volume 44, Issue 12, December 2009, Pages 5071-5079, doi:10.1016/j.ejmech.2009.09.012

The synthesis and the study of new amodiaquine derivatives bearing modified lateral basic chains as new agents with both antimalarial and antileishmanial activities are reported.

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